17th Century Scientist Gives First Description of Alien Life: Hear Passages from Christiaan Huygens’ Cosmotheoros (1698)

Astro­bi­ol­o­gists can now extrap­o­late the evo­lu­tion­ary char­ac­ter­is­tics of pos­si­ble alien life, should it exist, giv­en the wealth of data avail­able on inter­plan­e­tary con­di­tions. But our ideas about aliens have drawn not from sci­ence but from what Adri­an Hor­ton at The Guardian calls “an engross­ing feed­back loop” of Hol­ly­wood films, comics books, and sci-fi nov­els. A lit­tle over three-hun­dred years ago — hav­ing nev­er heard of H.G. Wells or the X‑Files — Dutch sci­en­tist Chris­ti­aan Huy­gens answered the ques­tion of what alien life might look like in his work Cos­moth­e­o­ros, pub­lished after his death in 1698.

Every­one knows the names Galileo and Isaac New­ton, and near­ly every­one knows their major accom­plish­ments, but we find much less famil­iar­i­ty with Huy­gens, even though his achieve­ments “make him the great­est sci­en­tist in the peri­od between Galileo and New­ton,” notes the Pub­lic Domain Review.

Those achieve­ments include the dis­cov­ery of Saturn’s rings and its moon, Titan, the inven­tion of the first refract­ing tele­scope, a detailed map­ping of the Ori­on Neb­u­la, and some high­ly notable advance­ments in math­e­mat­ics. (Maybe we — Eng­lish speak­ers, that is — find his last name hard to pro­nounce?)

Huy­gens was a rev­o­lu­tion­ary thinker. After Coper­ni­cus, it became clear to him that “our plan­et is just one of many,” as schol­ar Hugo A. van den Berg writes, “and not set apart by any spe­cial con­sid­er­a­tion oth­er than the acci­den­tal fact that we hap­pen to be its inhab­i­tants.” Using the pow­ers of obser­va­tion avail­able to him, he the­o­rized that the inhab­i­tants of Jupiter and Sat­urn (he used the term “Plan­e­tar­i­ans”) must pos­sess “the Art of Nav­i­ga­tion,” espe­cial­ly “in hav­ing so many Moons to direct their Course…. And what a troop of oth­er things fol­low from this allowance? If they have Ships, they must have Sails and Anchors, Ropes, Pil­lies, and Rud­ders…”

“We may well laugh at Huy­gens,” van den Berg writes, “But sure­ly in our own cen­tu­ry, we are equal­ly parochial in our own way. We invari­ably fail to imag­ine what we fail to imag­ine.” Our ideas of aliens fly­ing space­craft already seem quaint giv­en mul­ti­ver­sal and inter­di­men­sion­al modes of trav­el in sci­ence fic­tion. Huy­gens had no cul­tur­al “feed­back loop.” He was mak­ing it up as he went. “In con­trast to Huy­gens’ astro­nom­i­cal works, Cos­moth­e­o­ros is almost entire­ly spec­u­la­tive,” notes van den Berg — though his spec­u­la­tions are through­out informed and guid­ed by sci­en­tif­ic rea­son­ing.

To under­mine the idea of Earth as spe­cial, cen­tral, and unique, “a thing that no Rea­son will per­mit,” Huy­gens wrote — meant pos­ing a poten­tial threat to “those whose Igno­rance or Zeal is too great.” There­fore, he willed his broth­er to pub­lish Cos­moth­e­o­ros after his death so that he might avoid the fate of Galileo. Already out of favor with Louis XIV, whom Huy­gens had served as a gov­ern­ment sci­en­tist, he wrote the book while back at home in The Hague, “fre­quent­ly ill with depres­sions and fevers,” writes the Pub­lic Domain Review. What did Huy­gens see in his cos­mic imag­i­na­tion of the sail­ing inhab­i­tants of Jupiter and Sat­urn? Hear for your­self above in a read­ing of Huy­gens’ Cos­moth­e­o­ros from Voic­es of the Past.

Huy­gens’ descrip­tions of intel­li­gent alien life derive from his lim­it­ed obser­va­tions about human and ani­mal life, and so he pro­pos­es the neces­si­ty of human-like hands and oth­er appendages, and rules out such things as an “elephant’s pro­boscis.” (He is par­tic­u­lar­ly fix­at­ed on hands, though some alien humanoids might also devel­op wings, he the­o­rizes.) Like all alien sto­ries to come, Huy­gens’ spec­u­la­tions, how­ev­er log­i­cal­ly he presents them, say “more about our­selves,” as Hor­ton writes, “our fears, our anx­i­eties, our hope, our adapt­abil­i­ty — than any poten­tial out­side vis­i­tor.” His descrip­tions show that while he did not need to place Earth at the cen­ter of the cos­mos, he mea­sured the cos­mos accord­ing to a very human scale.

Relat­ed Con­tent:

What Do Aliens Look Like? Oxford Astro­bi­ol­o­gists Draw a Pic­ture, Based on Dar­win­ian The­o­ries of Evo­lu­tion

Carl Sagan Sent Music & Pho­tos Into Space So That Aliens Could Under­stand Human Civ­i­liza­tion (Even After We’re Gone)

Richard Feyn­man: The Like­li­hood of Fly­ing Saucers

Josh Jones is a writer and musi­cian based in Durham, NC. Fol­low him at @jdmagness

Benedict Cumberbatch Reads “the Best Cover Letter Ever Written”

In the 1930s, many a writer jour­neyed to Hol­ly­wood in order to make his for­tune. The screen­writer’s life did­n’t sit well with some of them — just ask F. Scott Fitzger­ald or William Faulkn­er — but a fair few made more than a go of it out West. Take the Bal­ti­more-born Robert Pirosh, whose stud­ies at the Sor­bonne and the Uni­ver­si­ty of Berlin land­ed him a job as a copy­writer in New York. This work seems to have proven less than sat­is­fac­to­ry, as evi­denced by the piece of cor­re­spon­dence that, still in his ear­ly twen­ties, he wrote and sent to “as many direc­tors, pro­duc­ers and stu­dio exec­u­tives as he could find.” It was­n’t just a request for work; it was what Let­ters Live today calls “the best cov­er let­ter ever writ­ten.”

Pirosh’s impres­sive mis­sive, which you can hear read aloud by favorite Let­ters Live per­former Bene­dict Cum­ber­batch in the video above, runs, in full, as fol­lows:

Dear Sir:

I like words. I like fat but­tery words, such as ooze, turpi­tude, gluti­nous, toady. I like solemn, angu­lar, creaky words, such as strait­laced, can­tan­ker­ous, pecu­nious, vale­dic­to­ry. I like spu­ri­ous, black-is-white words, such as mor­ti­cian, liq­ui­date, ton­so­r­i­al, demi-monde. I like suave “V” words, such as Sven­gali, svelte, bravu­ra, verve. I like crunchy, brit­tle, crack­ly words, such as splin­ter, grap­ple, jos­tle, crusty. I like sullen, crabbed, scowl­ing words, such as skulk, glow­er, scab­by, churl. I like Oh-Heav­ens, my-gra­cious, land’s‑sake words, such as tricksy, tuck­er, gen­teel, hor­rid. I like ele­gant, flow­ery words, such as esti­vate, pere­gri­nate, ely­si­um, hal­cy­on. I like wormy, squirmy, mealy words, such as crawl, blub­ber, squeal, drip. I like snig­gly, chuck­ling words, such as cowlick, gur­gle, bub­ble and burp.

I like the word screen­writer bet­ter than copy­writer, so I decid­ed to quit my job in a New York adver­tis­ing agency and try my luck in Hol­ly­wood, but before tak­ing the plunge I went to Europe for a year of study, con­tem­pla­tion and hors­ing around.

I have just returned and I still like words.

May I have a few with you?

Though not known as an unsub­tle actor, Cum­ber­batch seizes the oppor­tu­ni­ty to deliv­er each and every one of these choice words with its own vari­ety of exag­ger­at­ed rel­ish. Though none of these terms is espe­cial­ly recher­ché on its own, they must col­lec­tive­ly have giv­en the impres­sion of a for­mi­da­ble mas­tery of the Eng­lish lan­guage, espe­cial­ly to the ear of the aver­age Hol­ly­wood big-shot. One way or anoth­er, Pirosh’s let­ter did the trick: accord­ing to Let­ters of Note, it “secured him three inter­views, one of which led to his job as a junior writer at MGM. Fif­teen years lat­er,” he “won an Acad­e­my Award for Best Orig­i­nal Screen­play for his work on the war film Bat­tle­ground.”

A World War II pic­ture, Bat­tle­ground was writ­ten at least in part from Pirosh’s own expe­ri­ence: a few years into his Hol­ly­wood career, he enlist­ed and made a return to Europe, this time as a Mas­ter Sergeant in the 320th Reg­i­ment, 35th Infantry Divi­sion, see­ing action in France and Ger­many. After the war he went right back to writ­ing and pro­duc­ing, remain­ing active in the enter­tain­ment indus­try until at least the 1970s (and in fact, his writ­ing cred­its include con­tri­bu­tions to such pro­grams that defined that decade as Man­nixBarn­a­by Jones, and Hawaii Five‑O). Pirosh’s was an envi­able 20th-cen­tu­ry career, and one that began with a suit­ably brazen — and still con­vinc­ing — 20th-cen­tu­ry adver­tise­ment for him­self.

Relat­ed Con­tent:

Hunter S. Thompson’s Ball­sy Job Appli­ca­tion Let­ter (1958)

Bene­dict Cum­ber­batch Reads Kurt Vonnegut’s Incensed Let­ter to the High School That Burned Slaugh­ter­house-Five

Bene­dict Cum­ber­batch Reads Kurt Vonnegut’s Let­ter of Advice to Peo­ple Liv­ing in the Year 2088

Bene­dict Cum­ber­batch Reads a Let­ter Alan Tur­ing Wrote in “Dis­tress” Before His Con­vic­tion For “Gross Inde­cen­cy”

Bene­dict Cum­ber­batch Reads Albert Camus’ Touch­ing Thank You Let­ter to His Ele­men­tary School Teacher

“Stop It and Just DO”: Bene­dict Cum­ber­batch Reads Advice on Over­com­ing Cre­ative Blocks, Writ­ten by Sol LeWitt to Eva Hesse (1965)

Based in Seoul, Col­in Mar­shall writes and broad­casts on cities, lan­guage, and cul­ture. His projects include the Sub­stack newslet­ter Books on Cities, the book The State­less City: a Walk through 21st-Cen­tu­ry Los Ange­les and the video series The City in Cin­e­ma. Fol­low him on Twit­ter at @colinmarshall or on Face­book.

Medieval Scribes Discouraged Theft of Manuscripts by Adding Curses Threatening Death & Damnation to Their Pages

I’ve con­clud­ed that one shouldn’t lend a book unless one is pre­pared to part with it for good. But most books are fair­ly easy to replace. Not so in the Mid­dle Ages, when every man­u­script count­ed as one of a kind. Theft was often on the minds of the scribes who copied and illus­trat­ed books, a labo­ri­ous task requir­ing lit­er­al hours of blood, sweat and tears each day.

Scrib­al copy­ing took place “only by nat­ur­al light — can­dles were too big a risk to the books,” Sarah Laskow writes at Atlas Obscu­ra. Bent over dou­ble, scribes could not let their atten­tion wan­der. The art, one scribe com­plained, “extin­guish­es the light from the eyes, it bends the back, it crush­es the vis­cera and the ribs, it brings forth pain to the kid­neys, and weari­ness to the whole body.”

The results deserved high secu­ri­ty, and Medieval monks “did not hes­i­tate to use the worst pun­ish­ments they knew” for man­u­script theft, writes Laskow, name­ly threats of “excom­mu­ni­ca­tion from the church and hor­ri­ble, painful death.”

 

Theft deter­rence came in the form of inge­nious curs­es, writ­ten into the man­u­scripts them­selves, going “back to the 7th cen­tu­ry BCE,” Rebec­ca Rom­ney writes at Men­tal Floss. Appear­ing “in Latin, ver­nac­u­lar Euro­pean lan­guages, Ara­bic, Greek, and more,” they came in such cre­ative fla­vors as death by roast­ing, as in a Bible copied in Ger­many around 1172: “If any­one steals it: may he die, may he be roast­ed in a fry­ing pan, may the falling sick­ness [epilep­sy] and fever attack him, and may he be rotat­ed [on the break­ing wheel] and hanged. Amen.”

A few hun­dred years lat­er, a man­u­script curse from 15th-cen­tu­ry France also promis­es roast­ing, or worse:

Who­ev­er steals this book
Will hang on a gal­lows in Paris,
And, if he isn’t hung, he’ll drown,
And, if he doesn’t drown, he’ll roast,
And, if he doesn’t roast, a worse end will befall him.

The pluck­ing out of eyes also appears to have been a theme. “Who­ev­er to steal this vol­ume tries, Out with his eyes, out with his eyes!” warns the final cou­plet in a 13th-cen­tu­ry curse from a Vat­i­can Library man­u­script. Anoth­er curse in verse, found by author Marc Dro­gin, author of Anath­e­ma! Medieval Scribes and the His­to­ry of Book Curs­es, gets espe­cial­ly graph­ic with the eye goug­ing:

To steal this book, if you should try,
It’s by the throat you’ll hang high.
And ravens then will gath­er ’bout
To find your eyes and pull them out.
And when you’re scream­ing ‘oh, oh, oh!’
Remem­ber, you deserved this woe.

The hoped-for con­se­quences were not always so grim­ly humor­ous. “Grue­some as these pun­ish­ments seem,” the British Library writes, “to most medieval read­ers the worst curs­es were those that put the eter­nal fate of their souls at risk rather than their bod­i­ly health.” These would often be marked with the Greek word “Anath­e­ma,” some­times “fol­lowed by the Ara­ma­ic for­mu­la ‘Maranatha’ (‘Come, Lord!’).” Both appear in a curse added to a man­u­script of let­ters and ser­mons from Lesnes Abbey. Yet, unlike most medieval curs­es, here the thief is giv­en a chance to make resti­tu­tion. “Any­one who removes it or does dam­age to it: if the same per­son does not repay the church suf­fi­cient­ly, may he be cursed.”

Curs­es were not the only secu­ri­ty solu­tions of man­u­script cul­ture. Medieval monks also used book chains and locked chests to secure the fruit of their hard labor. As the old say­ing goes, “trust in God, but tie your camel.” But if locks and divine prov­i­dence should fail, scribes trust­ed that the fear of pun­ish­ment – even eter­nal damna­tion — down the road would be enough to make would-be book thieves think again.

Relat­ed Con­tent:

160,000+ Medieval Man­u­scripts Online: Where to Find Them

The Illu­mi­nat­ed Man­u­scripts of Medieval Europe: A Free Online Course from the Uni­ver­si­ty of Col­orado

Why Butt Trum­pets & Oth­er Bizarre Images Appeared in Illu­mi­nat­ed Medieval Man­u­scripts

Josh Jones is a writer and musi­cian based in Durham, NC. Fol­low him at @jdmagness

The Life & Music of the Godmother of Rock and Roll, Sister Rosetta Tharpe

When I was a wee lad I was inter­est­ed in the his­to­ry of rock and roll. Where did it come from? Who start­ed it? But also when I was wee, there didn’t seem to be a lot of infor­ma­tion around, cer­tain­ly not in my library down­town. But when Mud­dy Waters died in 1983, I start­ed to under­stand that rock and roll was sped-up blues, and pieces start­ed to slot togeth­er. How­ev­er, women weren’t part of the equa­tion. (Blame Rolling Stone Mag­a­zine).

That’s a long way of say­ing the Sis­ter Roset­ta Tharpe should be bet­ter known than she is, espe­cial­ly as one dubbed the God­moth­er of Rock and Roll. Play­ing scratchy, dis­tort­ed elec­tric gui­tar and singing as if on a direct line to heav­en, Tharpe would go on to influ­ence every­body from Elvis Pres­ley to Chuck Berry, and every­body who came after her. So why is she not more of a house­hold name?

The 2011 BBC doc­u­men­tary above (split into four 15-minute chunks) resus­ci­tates a leg­end who not only played a mean gui­tar but set the stan­dard for the gospel-crossover artist, mak­ing a name on the gospel cir­cuit, but mak­ing her fame in the sec­u­lar night­clubs of Amer­i­ca. Tharpe’s dis­tinc­tion is that she returned to gospel with­out los­ing any of her edge.

A pre­co­cious young­ster in Arkansas dur­ing the ear­ly 1920s, she became the star of her Pen­te­costal church start­ing at four years old. Raised by her moth­er, then forced into an arranged mar­riage at 19-years-old to an old­er preach­er, Thomas Tharpe, she kept his name when she left their abu­sive mar­riage. She and her moth­er relo­cat­ed to Chica­go, where blues and jazz were inter­min­gling in a hot­house cul­ture. Dec­ca signed her, and although she told her church­go­ing friends that she had to sing these sec­u­lar songs because of that darned sev­en-year con­tract, Tharpe rose to fame quick­ly. The footage of her singing in front of the Cot­ton Club band led by Lucky Millinder is one of a cheeky, charm­ing 23 year old.

As the doc makes clear, Tharpe had a rebel­lious streak, didn’t do what she was told, and pushed bound­aries in a very seg­re­gat­ed Amer­i­ca. She invit­ed the all-white Jor­danaires to tour with her, sur­pris­ing house man­agers and book­ing agents alike. And she car­ried on a love affair and cre­ative part­ner­ship with fel­low gospel singer Marie Knight for decades, very much on the down low.

So per­haps this is the rea­son Tharpe has not been on our col­lec­tive radar—we’ve been slow to admit that rock gui­tar was cre­at­ed by a queer black woman devot­ed to the Lord. Nobody in the audi­ence knew this, though, at the aban­doned rail­way sta­tion at Wilbra­ham Road, Man­ches­ter, in May 1964. On one side of the station’s tracks, British teenagers were gath­ered to hear raw, rock and roll from Amer­i­ca. On the oth­er side, Tharpe stands with her gui­tar, wear­ing a thick coat to pro­tect her from the spring rain. Backed by her band, she chan­nels a holy force and sings about the rain of the Great Flood, the lyrics abstract and repet­i­tive, as if in a trance. The footage opens the doc­u­men­tary and makes as good a case as any of why Tharpe should be part of the pan­theon of rock roy­al­ty. (You can see the whole clip here.) Back in the States, Tharpe had been eclipsed by Mahalia Jack­son, but the Brits didn’t know any of that. They just sense they’ve tapped into one of the sources for the music explod­ing around them.

It took until 2018 for Tharpe to be induct­ed into the Rock & Roll Hall of Fame, years after all those white boy copy­cats. Now is the time to re-dis­cov­er her and hear what you’ve been miss­ing.

Relat­ed Con­tent:

New Web Project Immor­tal­izes the Over­looked Women Who Helped Cre­ate Rock and Roll in the 1950s

An Intro­duc­tion to Sis­ter Roset­ta Tharpe

Mud­dy Waters and Friends on the Blues and Gospel Train, 1964

Watch the Hot Gui­tar Solos of Sis­ter Roset­ta Tharpe

Revis­it The Life & Music of Sis­ter Roset­ta Tharpe: ‘The God­moth­er of Rock and Roll’

The Women of Rock: Dis­cov­er an Oral His­to­ry Project That Fea­tures Pio­neer­ing Women in Rock Music

Ted Mills is a free­lance writer on the arts who cur­rent­ly hosts the Notes from the Shed pod­cast and is the pro­duc­er of KCR­W’s Curi­ous Coast. You can also fol­low him on Twit­ter at @tedmills, and/or watch his films here.

Saying Goodbye to Charlie Watts (RIP), the Engine of the Rolling Stones for Half a Century

Char­lie Watts, the Rolling Stones’ icon­ic drum­mer since 1962, passed away yes­ter­day from unspec­i­fied caus­es at the age of 80. His death is a great loss for rock and roll. “When Char­lie Watts dies, the beat stops,” Rob Harvil­la writes at the Ringer, “nev­er to be played again with such mes­mer­iz­ing force, with such ultra-suave propul­sion, with such casu­al­ly indomitable rad­ness.” These are not tech­ni­cal terms, and Watts was not a tech­ni­cal drum­mer. “I’m not a para­did­dle man,” he said in 2000. “It’s not tech­ni­cal, it’s emo­tion­al. One of the hard­est things of all is to get that feel­ing across.”

Watts per­fect­ed the inde­fin­able feel of rock and roll by way of jazz, play­ing along to his favorite records by Char­lie Park­er — first with a set of wire brush­es on an unstrung ban­jo, then on the first drum kit his father bought him.

From the greats, he learned to swing and mas­tered dynam­ics. The com­mand­ing mar­tial crack of Watts’ snare held a band of mot­ley pirates togeth­er — with­out him, the Stones might have dis­solved into a col­lec­tion of preen­ing antics and wan­der­ing blues licks; with him at the cen­ter, they coa­lesced into a team. “I don’t know how the hell that old suck­er got to be so good,” Keef mar­veled.

Watts would be the last one to talk about how good he was — he hat­ed inter­views and star­dom in gen­er­al. “I’ve nev­er been inter­est­ed in all that stuff and still am not,” he said. “I don’t know what show­biz is and I’ve nev­er watched MTV. There are peo­ple who just play instru­ments, and I’m pleased to know that I’m one of them.” His sin­gu­lar focus came from lis­ten­ing intent­ly to what oth­ers were doing, as he says in the inter­view at the top, and copy­ing what they did, a method he calls “one of my flaws…. I learned by watch­ing.” But the means by which Watts learned to play made him the per­fect drum­mer for the Stones. He watched, lis­tened, learned the songs, then played them per­fect­ly in tune with the band, keep­ing them in time while respond­ing dynam­i­cal­ly to Richards and Jagger’s inter­play.

“I should have gone to school and learned how to do it,” Watts says, with typ­i­cal self-dep­re­ca­tion. Instead, he made his school the jazz clubs of Lon­don and Paris, where he went to see Bud Pow­ell’s drum­mer Ken­ny Clark. Just as he’d done in his room on his first drum kit, he lis­tened intent­ly and copied what he heard. Watts looked like a man who stood apart from the band, with his world-weary expres­sion, end­less col­lec­tion of sharp suits and reserved demeanor. But when he played with the Stones, they locked togeth­er. It was love, he said, “I love this band.”

His life was a tes­ta­ment to the vital­i­ty of the music that made him, at 80, still want to go back on the road after announc­ing just two weeks ago that he’d have to sit out this year’s tour. Forty years ago, Watts couldn’t fore­see the band he helped make world famous last­ing very much longer. “I nev­er thought it would last five min­utes,” he said in 1981, “but I fig­ured I’d live that five min­utes to the hilt because I love them. They’re big­ger than I am if you real­ly want to know. I admire them, I like them as friends, I argue with them and I love them…. I don’t real­ly care if it stops…. “ Now that he’s gone, it’s hard to see how the Stones can go on.

As near­ly every mem­ber of the band, espe­cial­ly Richards, has said at one time or anoth­er, no Char­lie Watts, no Rolling Stones. “Charlie’s the engine,” said Ron­nie Wood in the Stones doc­u­men­tary Tip of the Tongue. “We don’t go any­where with­out the engine.” Wher­ev­er they go now, there’s no ques­tion the Rolling Stones would have been a dif­fer­ent band entire­ly with­out him. See some of his best live moments in the clips above and learn what Char­lie him­self thought of his play­ing in the short doc­u­men­tary at the top, “If It Ain’t Got That Swing,” a record of his approach to drum­ming and life in gen­er­al that cap­tures the true spir­it of a rock leg­end.

Relat­ed Con­tent: 

A Char­lie Watts-Cen­tric View of the Rolling Stones: Watch Mar­tin Scorsese’s Footage of Char­lie & the Band Per­form­ing “Jumpin’ Jack Flash” and “All Down the Line”

Rolling Stones Drum­mer Char­lie Watts Writes a Children’s Book Cel­e­brat­ing Char­lie Park­er (1964)

A Visu­al His­to­ry of The Rolling Stones Doc­u­ment­ed in a Beau­ti­ful, 450-Page Pho­to Book by Taschen

The Sto­ry of the Rolling Stones: A Selec­tion of Doc­u­men­taries on the Quin­tes­sen­tial Rock-and-Roll Band

Josh Jones is a writer and musi­cian based in Durham, NC. Fol­low him at @jdmagness

How the COVID-19 Vaccines Could Be Created So Quickly: Two Animated Videos Explain the How mRNA Vaccines Were Developed, and How They Work

The world now has COVID-19 vac­cines, of which more and more peo­ple are receiv­ing their dos­es every day. A year and a half ago the world did not have COVID-19 vac­cines, though it was fast becom­ing clear how soon it would need them. The sub­se­quent devel­op­ment of the ones now being deployed around the world took not just less than a year and a half but less than a year, an impres­sive speed even to many of us who nev­er dug deep into med­ical sci­ence. The achieve­ment owes in part to the use of mRNA, a term most of us may recall only dim­ly from biol­o­gy class­es; through the pan­dem­ic, mes­sen­ger ribonu­cle­ic acid, to use its full name, has proven if not the sav­ior of human­i­ty, then at least the very mol­e­cule we need­ed.

One should­n’t get “the idea that these vac­cines came out of nowhere.” On Twit­ter, Dan Rather — these days a more out­spo­ken  fig­ure than ever — calls the preva­lence such a notion “a fail­ure of sci­ence com­mu­ni­ca­tion with trag­ic results,” describ­ing the vac­cines as “the result of DECADES of basic research in MULTIPLE fields build­ing on the BREADTH and DEPTH of human knowl­edge.”

You can get a clear­er sense of what that research has involved through videos like the ani­mat­ed TED-Ed explain­er above. “In the twen­ti­eth cen­tu­ry, most vac­cines took well over a decade to research, test, and pro­duce,” says its nar­ra­tor. “But the vac­cines for COVID-19 cleared the thresh­old for use in less than eleven months.” The “secret”? mRNA.

A “nat­u­ral­ly occur­ring mol­e­cule that encodes the instruc­tions for occur­ring pro­teins,” mRNA can be used in vac­cines to “safe­ly intro­duce our body to a virus.” Researchers first “encode tril­lions of mRNA mol­e­cules with instruc­tions for a spe­cif­ic viral pro­tein.” Then they inject those mol­e­cules into a spe­cial­ly designed “nanopar­ti­cle” also con­tain­ing lipids, sug­ars, and salts. When it reach­es our cells, this nanopar­ti­cle trig­gers our immune response: the body pro­duces “anti­bod­ies to fight that viral pro­tein, that will then stick around to defend against future COVID-19 infec­tions.” And all of this hap­pens with­out the vac­cine alter­ing out DNA,

While mRNA vac­cines will “have a big impact on how we fight COVID-19,” says the nar­ra­tor of the Vox video above, “their real impact is just begin­ning.” Their devel­op­ment marked “a turn­ing point for the pan­dem­ic,” but giv­en their poten­tial appli­ca­tions in the bat­tles against a host of oth­er, even dead­lier dis­eases (e.g., HIV), “the pan­dem­ic might also be a turn­ing point for vac­cines.”

Relat­ed Con­tent:

How Fast Can a Vac­cine Be Made?: An Ani­mat­ed Intro­duc­tion

How Do Vac­cines (Includ­ing the COVID-19 Vac­cines) Work?: Watch Ani­mat­ed Intro­duc­tions

How Vac­cines Improved Our World In One Graph­ic

19th Cen­tu­ry Maps Visu­al­ize Measles in Amer­i­ca Before the Mir­a­cle of Vac­cines

Roald Dahl, Who Lost His Daugh­ter to Measles, Writes a Heart­break­ing Let­ter about Vac­ci­na­tions: “It Is Almost a Crime to Allow Your Child to Go Unim­mu­nised”

Yo-Yo Ma Plays an Impromp­tu Per­for­mance in Vac­cine Clin­ic After Receiv­ing 2nd Dose

Based in Seoul, Col­in Mar­shall writes and broad­casts on cities, lan­guage, and cul­ture. His projects include the Sub­stack newslet­ter Books on Cities, the book The State­less City: a Walk through 21st-Cen­tu­ry Los Ange­les and the video series The City in Cin­e­ma. Fol­low him on Twit­ter at @colinmarshall or on Face­book.

A Harp Played with a Heavy Distortion Pedal

You’ve had the thought exper­i­ment in your head. What would hap­pen if you run a harp through a heavy dis­tor­tion ped­al? Now you can see how it all plays out. Emi­ly Hop­kins has been play­ing the harp for over 20 years and has recent­ly tak­en to exper­i­ment­ing with harp dis­tor­tion. Above, you can watch her exper­i­ment with the Nepenthes by Elec­tro­foods, the heav­i­est dis­tor­tion ped­al she could find. Oth­er ped­al dis­tor­tion exper­i­ments can be found here.

If you would like to sign up for Open Culture’s free email newslet­ter, please find it here. Or fol­low our posts on Threads, Face­book, BlueSky or Mastodon.

If you would like to sup­port the mis­sion of Open Cul­ture, con­sid­er mak­ing a dona­tion to our site. It’s hard to rely 100% on ads, and your con­tri­bu­tions will help us con­tin­ue pro­vid­ing the best free cul­tur­al and edu­ca­tion­al mate­ri­als to learn­ers every­where. You can con­tribute through Pay­Pal, Patre­on, and Ven­mo (@openculture). Thanks!

Relat­ed Con­tent: 

A Brief His­to­ry of Gui­tar Dis­tor­tion: From Ear­ly Exper­i­ments to Hap­py Acci­dents to Clas­sic Effects Ped­als

Two Gui­tar Effects That Rev­o­lu­tion­ized Rock: The Inven­tion of the Wah-Wah & Fuzz Ped­als

Visu­al­iz­ing Bach: Alexan­der Chen’s Impos­si­ble Harp

Pink Floyd Songs Played Splen­did­ly on a Harp Gui­tar: “Com­fort­ably Numb,” “Wish You Were Here” & More

Dying in the Name of Vaccine Freedom

Here’s the con­text to a sober­ing new­ly-released video from The New York Times:

In the video above, Alexan­der Stock­ton, a pro­duc­er on the Opin­ion Video team, explores two of the main rea­sons the num­ber of Covid cas­es is soar­ing once again in the Unit­ed States: vac­cine hes­i­tan­cy and refusal.

“It’s hard to watch the pan­dem­ic drag on as Amer­i­cans refuse the vac­cine in the name of free­dom,” he says.

Seek­ing under­stand­ing, Mr. Stock­ton trav­els to Moun­tain Home, Ark., in the Ozarks, a region with gal­lop­ing con­ta­gion and — not unre­lat­ed — abysmal vac­ci­na­tion rates.

He finds that a range of feel­ings and beliefs under­pins the low rates — includ­ing fear, skep­ti­cism and a lib­er­tar­i­an strain of defi­ance.

This doubt even extends to the staff at a region­al hos­pi­tal, where about half of the med­ical per­son­nel are not vac­ci­nat­ed — even while the inten­sive care unit is crowd­ed with unvac­ci­nat­ed Covid patients fight­ing for their lives.

Moun­tain Home — like the Unit­ed States as a whole — is caught in a tug of war between pri­vate lib­er­ty and pub­lic health. But Mr. Stock­ton sug­gests that unless gov­ern­ment upholds its duty to pro­tect Amer­i­cans, keep­ing the com­mon good in mind, this may be a bat­tle with no end.

Sober­ing indeed…

Relat­ed Con­tent 

How the COVID-19 Vac­cines Could Be Cre­at­ed So Quick­ly: Two Ani­mat­ed Videos Explain the How mRNA Vac­cines Were Devel­oped, and How They Work

MIT Presents a Free Course on the COVID-19 Pan­dem­ic, Fea­tur­ing Antho­ny Fau­ci & Oth­er Experts

Mattel’s Bar­bie Turns Women of Med­i­cine, Includ­ing COVID Vac­cine Devel­op­er, Into Dolls

A Bio­sta­tis­ti­cian Uses Cro­chet to Visu­al­ize the Fright­en­ing Infec­tion Rates of the Coro­n­avirus

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